FERROPTOSIS SUPPRESSOR PROTEIN 1 INHIBITION PROMOTES TUMOR FERROPTOSIS AND ANTI-TUMOR IMMUNE RESPONSES IN LIVER CANCERSUMMARY

Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver CancerSummary

Background & Aims: Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with dreadful clinical outcome.Tyrosine kinase inhibitors and immune checkpoint inhibitors are the only United States Food and Drug Administration-approved therapeutic options for patients with advanced HCC with limited therapeutic success.Ferroptosis is a form

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The Canadian Healthy Life Trajectories Initiative (HeLTI) Trial: a study protocol for monitoring fidelity of a preconception-lifestyle behaviour intervention

Abstract Background In evaluating technology-based behaviour change interventions, it is increasingly important to have a monitoring plan for intervention fidelity.It is important to maintain intervention fidelity to ensure that the theory-based intervention that is being tested is what causes the observed changes, particularly for eHealth behaviou

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